By and For the Interventional Cardiovascular Community. Sharing knowledge, experience and practice in cardiovascular interventional medicine

What’s new in the 2025 guidance on valvular heart disease - ESC Congress 2025

In this interview, Alex Sticchi speaks with Fabien Praz and Michael Borger, co-chairs of the 2025 ESC/EACTS Valvular Guidelines Task Force.

03 Sep 2025

DAPT-SHOCK-AMI

The DAPT-SHOCK-AMI study was designed to provide the first randomised evidence to address the uncertainty around the potential benefit of IV Cangrelor in AMICS

03 Sep 2025

Key updates in valvular heart disease management: insights from the 2025 ESC/EACTS Guidelines

The newly released guidelines mark a major evolution in practice, shifting toward earlier interventions, greater use of transcatheter therapies, streamlined imaging and antithrombotic strategies, and a stronger role for Heart Teams and Heart Valve Networks.

03 Sep 2025

TACSI

This R-RCT aimed to investigate among patients undergoing CABG after ACS, whether 12 months of ticagrelor + aspirin (DAPT) reduced clinical events as compared to aspirin alone, with respect to a composite major adverse cardiac events MACE.

02 Sep 2025

NEO-MINDSET

Immediate aspirin withdrawal after PCI in ACS patients failed to show noninferiority of potent P2Y12 inhibitor monotherapy versus DAPT, with early excess ischemic events despite reduced bleeding. These findings suggest that at least 1 month of DAPT remains safer than immediate monotherapy.

03 Sep 2025

OPINION trial

Prophylactic SLAAO during valve surgery in patients without pre-operative AF did not show clear benefit at 1 year, with results limited by a younger, lower-risk population and short follow-up. Routine use in this setting cannot be recommended, highlighting the need for longer-term data.

PCR Submissions: key dates

PCR London Valves and PCR Tokyo Valves Calls for submissions are open! Share your Scientific Abstracts, Clinical Cases, Late-Breaking Trials or Innovations and take the stage in London or Tokyo! Help shape the future of the field — don’t miss this opportunity.

Journal Club

OCT- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial 1- versus 3-month DAPT after EES implantation in HBR diabetic patients: results from the XIENCE Short DAPT programme Outcomes after CABG compared with FFR-guided PCI in patients presenting with ACS

PCR WEBINARS

PCR Rio Valves

Registrations are officially open for PCR Rio Valves 2025! Connect with the global interventional community in Rio de Janeiro for cutting-edge insights, LIVE Educational Cases, and Heart Team sessions.

Programmes are out

Aortic valvar complex

Understanding the anatomy of the aortic valvar complex is important: from the aortic root, aortic sinuses, sinotubular junction, aortic leaflets, anatomy of the so-called "Aortic Annulus" and more…

My Toolkit

How to perform angiographic check after large-sheath removal in single access procedures

Learn how to perform antegrade angiography post-large-sheath removal, aiding in prompt identification and management of vascular complications like arterial damage and hemostasis failure.