Christopher Allen

Christopher Allen

Interventional cardiologist / Cardiologist
St. Thomas' Hospital - London, United Kingdom

Latest contributions

Transcatheter tricuspid valve replacement: LIVE Educational Case from St. Thomas' Hospital - London, UK

18 Nov 2025 – From PCR London Valves 2025

This educational session presents a live transcatheter tricuspid valve replacement case from St. Thomas' Hospital, London, complemented by detailed patient imaging analysis and operator strategy. Additionally, a recorded case from the Upper Silesian Medical Center in Poland provides further insights into procedural nuances and outcomes, offering...

TAVI for aortic regurgitation in high surgical risk: outcomes in 700 patients from ALIGN-AR

16 Nov 2025 – From PCR London Valves 2025

Christopher Allen and Raj Makkar sit down to review the ALIGN-AR trial and its implications for treating native aortic regurgitation. 

ALIGN-AR was a pivotal, single-arm, multicenter investigational study designed to evaluate a dedicated transcatheter solution in patients with moderate-to-severe native AR who were considered high risk for...

Outcomes in 700 patients from ALIGN-AR regarding TAVI for AR in high surgical risk

TARGET study interim results: safety and performance of Cardiovalve replacement system for tricuspid regurgitation

16 Nov 2025 – From PCR London Valves 2025

Georg Nickenig and Christopher Allen discuss transcatheter replacement for the tricuspid valve and a dedicated transfemoral device in this interview, focusing on the TARGET study.

TARGET set out to answer two questions: can tricuspid regurgitation (TR) be reduced to mild or zero, and what are the safety...

TARGET study interim results: safety and performance of Cardiovalve replacement system for tricuspid regurgitation

One-year results from the ADALA trial

16 Nov 2025 – From PCR London Valves 2025

Left atrial appendage (LAA) closure is a new focus at this year’s PCR London Valves Course, and, in this interview, Xavier Freixa and Christopher Allen discuss the ADALA trial and its impact on post-occlusion management.

The study compared three months of low-dose DOAC with three months of...

One-year results from the ADALA tria

Tricuspid valve: PCR London Valves 2025 highlights

18 Nov 2025 – From PCR London Valves 2025

At PCR London Valves 2025, Course Directors Francesco Maisano and Nicolo Piazza highlight with Chris Allen the rapid evolution of tricuspid interventions. They emphasise advances in imaging and simulation, with dedicated labs offering practical multimodality training and hands-on experience. LIVE cases showcased both repair and replacement...

Tricuspid valve: PCR London Valves 2025 highlights

Mitral valve: PCR London Valves 2025 highlights

17 Nov 2025 – From PCR London Valves 2025

Together with Chris Allen, Course Directors Tiffany Patterson and Nina Wunderlich highlight the Mitral programme from PCR London Valves 2025. The Course began with fundamentals, including imaging and step-by-step procedural training, and then focused on complex cases, complications, and hands-on discussions. LIVE cases featured edge-to-edge repair,...

Mitral valve: PCR London Valves 2025 highlights

Five-year outcomes following early experience with transapical TMVR

16 Nov 2025 – From PCR London Valves 2025

In this discussion, Christopher Allen and Michael Reardon review the five-year results of an early transapical TMVR system implanted in very high-risk, inoperable patients.

The device showed sustained elimination of mitral regurgitation, with over 80% of patients maintaining trace or no MR at five years and no...

Five-year outcomes following early experience with transapical TMVR

Redo TAVI: LIVE Educational Case from Hospital Álvaro Cunqueiro - Vigo, Spain

16 Nov 2025 – From PCR London Valves 2025

This session presents an educational case on redo transcatheter aortic valve implantation (TAVI) from Hospital Álvaro Cunqueiro, Spain, featuring patient presentation, imaging analysis, operator strategy, and procedural nuances, complemented by a recorded case from Poland.

Acute and late coronary complications post-TAVI

21 May 2025 – From EuroPCR 2025

Gain insights into acute and late coronary complications following TAVI. This session discusses angina post-TAVI, mechanisms of acute severe mitral regurgitation during TAVR, hidden coronary obstructions, sudden hemodynamic collapse, and acute coronary occlusion after balloon aortic valvuloplasty.

Acute and late coronary complications post-TAVI

Tips for challenging TAVI scenarios

21 May 2025 – From EuroPCR 2025

Explore expert tips for navigating challenging TAVI scenarios including cases with stent entrapment, extremely large annuli, and rare anatomical conditions like Klippel Feil syndrome. Understand approaches for intraannular valve prosthesis implantation in complex coronary anatomy.

Tips for challenging TAVI scenarios

TAVI innovations: late-breaking trials from PCR London Valves 2024

24 Nov 2024 – From PCR London Valves 2024

What does the future hold for TAVI procedures? Don’t miss the latest innovations—watch this video now! It explores the Late-Breaking Trials from PCR London Valves 2024, featuring groundbreaking studies that could transform the way we approach TAVI in clinical practice.

You’ll dive into the CANNULATE TAVR EXTENDED...

TAVI innovations: late-breaking trials from PCR London Valves 2024

Rapid-fire - TAVI

24 Nov 2024 – From PCR London Valves 2024

Dive into this rapid-fire session showcasing selected PCR London Valves 2024 Clinical Cases submissions related to TAVI. Explore diverse and challenging TAVI scenarios, including TAVI in patients with cardiogenic shock, pure aortic regurgitation, and patient-prosthesis mismatch. Gain insights into troubleshooting techniques and strategies for navigating complex...

Rapid-fire - TAVI

Transcatheter mitral repair and replacement for primary mitral regurgitation - LIVE case

19 Nov 2023 – From PCR London Valves 2023

This session aims to highlight the remarkable advancements achieved in transcatheter mitral valve intervention over the past two decades, since its inception. Follow two TEER cases which illustrate this rapidly growing field:

  • Transcatheter edge-edge mitral valve repair
    A 77-year-old male with a history of SAVR (bioprothesis) + LIM-LAD/Diag, normal...
Transcatheter mitral valve intervention - 20 years on - LIVE case

Management of a patient with severe CAD and aortic valve stenosis

20 May 2022 – From EuroPCR 2022

Watch the LIVE case of an 87-year-old male patient with a history of hypertension and dyslipidemia but no other significant cardiovascular risk factors and remarkably good health for an elderly man, but with angina for some months and dyspnea, and discuss the management of TAVI candidates with...

Management of a patient with severe CAD and aortic valve stenosis

Left main bifurcation stenting

19 May 2022 – From EuroPCR 2022

Let's study, LIVE from Massy, France, the case of a 76-year-old man, hypertensive, dyslipidemic, who presented apical necrosis without ischemia in 2017, asymptomatic, referred for myocardial scintigraphy, and find out more about performing LM PCI, using imaging to guide the procedure.

Left main bifurcation stenting

TAVI in a patient with bicuspid anatomy

19 May 2022 – From EuroPCR 2022

How to perform TAVI in a patient with bicuspid anatomy? Watch this case LIVE from Massy, France, to try to get answers to key issues: sizing, implantation technique, valve choice, and lifetime management.

TAVI in a patient with bicuspid anatomy

PCR's Got Talent - Round 2 - Session 2

18 May 2022 – From EuroPCR 2022

View this session to discover the abstracts submitted during the second round of the second session of EuroPCR 2022 PCR's Got Talent, a unique abstract competition for young practitioners.

PCR's Got Talent - Round 2 - Session 2

PCR's Got Talent - Round 1 - Session 2

17 May 2022 – From EuroPCR 2022

Consult this session to discover a selection of cases presented during the round 1 of PCR's Got Talent at EuroPCR 2022: tricuspid regurgitation and right ventricular-pulmonary artery coupling, TAVI vs. medical therapy in patients with borderline severe classical LFLG AS, the LIRA sizing method of TAVR...

PCR's Got Talent - Round 1 - Session 2

Crash TAVI-in-TAVI complicated by coronary obstruction

20 Apr 2022

Thanks to this Image in Interventional Cardiology, view an emergency TAVI-in-TAVI for cardiogenic shock secondary to acute valve degeneration complicated by left main stem obstruction treated successfully by chimney stenting.

Right ventricular-pulmonary arterial coupling and afterload reserve in patients undergoing transcatheter tricuspid valve repair

10 Feb 2022

The authors hypothesized that disordered right ventricular to pulmonary artery (RV-PA) coupling may denote RV decompensation in patients undergoing transcatheter tricuspid valve repair (TTVR) that may correlate with poor clinical outcomes.

Christopher Allen

Reviewer

Christopher Allen

Reviewer

Alison Duncan

TAVI procedure planning and optimising patient outcomes

21 Nov 2021 – From PCR London Valves 2021

Watch this series of videos from PCR London Valves 2021 to evaluate whether TAVICT scans can replace invasive coronary angiography pre-TAVI, to appreciate how pre-operative computed tomography evaluation of aortic burden can predict acute kidney injury post-TAVR, and to appraise mortality in TAVI patients converted to...

TAVI procedure planning and optimising patient outcomes

PCI in a patient with prior TAVI - Session with LIVE demonstration

18 May 2021 – From EuroPCR 2021

Watch this session if you want to discuss the available data for treating coronary artery disease in patients undergoing TAVI and to understand the role of FFR/IFR in coronary artery disease assessment prior to TAVI.

This session was originally presented during EuroPCR 2021.

PCI in a patient with prior TAVI

TAVI in a patient with coronary artery disease - Session with LIVE demonstration

18 May 2021 – From EuroPCR 2021

Watch this session if you want to discuss the available data for treating coronary artery disease in patients undergoing TAVI and to understand the role of FFR/IFR in coronary artery disease assessment prior to TAVI.

This session was originally presented during EuroPCR 2021.

TAVI in a patient with coronary artery disease

What will be relevant for TAVI assessment in 2020?

19 Nov 2019 – From PCR London Valves 2019

Consult this session to learn all about what will be relevant for TAVI assessment in 2020: key imaging requirements before referral to the Heart Team, which patients may need a pacemaker and when it should be implanted, how modern Heart Teams should function, and more!

What will be relevant for TAVI assessment in 2020?